Effect of thrice a day vs once a day coconut oil application on growth parameters and nosocomial infection in preterm very low birthweight newborns A Randomised Control Trial
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 184
- 试验地点
- 1
- 主要终点
- determine whether babies in the oil massage group (thrice a day) have better growth parameters than babies without oil massage (once a day)
研究概览
简要总结
the skin of preterm very low birth weight babies lacks vernix and its antimicrobial properties and as the more premature the babies are the more immature the skin barrier. This leads to increased Transepidermal water loss leading to significant weight loss in premature babies.
Emollients like coconut oil, petroleum jelly,topical dressings decrease TEWL and form mechanical barrier to bacteria .
Coconut oil is used traditionally in India for Indian massage.
Presently there are very few studies evaluating the efficacy of coconut oil on growth of preterm infants.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 1.00 Day(s) 至 30.00 Day(s)（—）
- 性别
- All
入选标准
- •G.A less than 33 weeks and/or less than 1500 grams born in IMS and SUM hospital.
排除标准
- •Sick baby Presence of a major congenital anomaly; Any Major surgical procedure The mother had known immunodeficiency.
结局指标
主要结局
determine whether babies in the oil massage group (thrice a day) have better growth parameters than babies without oil massage (once a day)
时间窗: determine whether babies in the oil massage group (thrice a day) have better growth parameters than babies | without oil massage (once a day) at 4 weeks PNA
次要结局
- • To determine whether thrice daily application of coconut oil at first month of life significantly reduced incidence of nosocomial infection of preterm infants(4 weeks of post natal age)
研究者
Shonit kumar Patro
IMS and SUM hospital