跳至主要内容
临床试验/NCT00528463
NCT00528463已完成4 期

a Prospective Case Series of Pre-emptive Pre-amputation Sciatic Nerve Block to Prevent Lower Limb Phantom Pain

Université de Sherbrooke1 个研究点 分布在 1 个国家目标入组 17 人开始时间: 2005年1月1日最近更新:
适应症
干预措施

试验速览

阶段
4 期
状态
已完成
入组人数
17
试验地点
1
主要终点
incidence of lower limb phantom pain

研究概览

简要总结

Phantom limb pain is a complication of amputation. Although pre-empitve epidural analgesia was once thought to prevent such a com plication, recent studies did not demonstrate this. Peripheral blocks are more powerful then epidurals, and can even influence somatotropic representation in the brain. This a prospective case series in which the investigators hope to show a decrease, against historical control, of the incidence of post-operative amputation lower limb phantom pain. The investigators established the block at least 24 hours pre-operative and continue it for at least 2 days. Patient are followed daily for the 1st 3 days and then up to 3 month for the incidence of phantom limb pain. The investigators hope to recruit 30 patients.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Prevention
盲法
None

入排标准

性别
All
接受健康志愿者
否

入选标准

  • •Patient scheduled for lower limb amputation

排除标准

  • •Inability to consent
  • •Contraindication to peripheral nerve block
  • •Inability to perform the block
  • •Inadequate time frame (less than 24 hours prior to surgery)

研究组 & 干预措施

sciatic block

Experimental

One arm, all patient studied received a block

干预措施: sciatic nerve block (Procedure)

结局指标

主要结局

incidence of lower limb phantom pain

时间窗: 3 month post amputation

次要结局

未报告次要终点

研究者

申办方类型
Other

研究点 (1)

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