跳至主要内容
临床试验/CTRI/2025/06/088589
CTRI/2025/06/088589尚未招募3 期

"THE EFFICACY OF NITROGLYCERIN LINGUAL SPRAY 400MCG AND 800MCG IV LIGNOCAINE IN ATTENUATION OF PRESSOR RESPONSE FOLLOWING INTUBATION:A RANDOMISED CONTROLLED TRIAL".

SOMANATH R GOLAGI1 个研究点 分布在 1 个国家目标入组 75 人开始时间: 2025年6月25日最近更新:

试验速览

阶段
3 期
状态
尚未招募
发起方
入组人数
75
试验地点
1
主要终点
Prevention of PRESSOR RESPONSE FOLLOWING INTUBATION using lingual spray of drug

研究概览

简要总结

The Nitroglycerin  a potent hypotensive agent when it is used iv  . Laryngoscopy is essential  to do intratracheal  intubation to secure definitive Airway in patient undergoing Surgery under General anaesthesia. The inevitable pressure  response. Following intubation Haemodyanmic  changes so to minimise  these response ,risks and possible complications the lingual spray useful in preventing the pressure response of the Laryngoscopy  .The study calculate optimum dosage with comparison with other drug like lignocaine iv for reducing  response .

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Participant Blinded

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • Group of patients comes under American society of Anaesthesia 1 and 2 undergoing surgery under General anaesthesia.

排除标准

  • Obstetrics patients Childrens Allergic to drug any type of Allegies Any patient refusal.

结局指标

主要结局

Prevention of PRESSOR RESPONSE FOLLOWING INTUBATION using lingual spray of drug

时间窗: Prevention of PRESSOR RESPONSE FOLLOWING INTUBATION within minutes 1 min 2 min 5 min 10 min 15 min 20 min

次要结局

  • Nil Reduction in the pressure response following intubation(Might require higher doses a)

研究者

发起方
SOMANATH R GOLAGI
申办方类型
Government medical college
责任方
Principal Investigator
主要研究者

Dr Priyank V

BANGALORE MEDICAL COLLEGE AND RESEARCH INSTITUTE Bengaluru

研究点 (1)

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