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临床试验/NCT03393650
NCT03393650已完成不适用

Effect of Protein Supplementation Combined With Mixed Power Training on Muscle Function, Composition, Phenotype and Functional Capacities Compared to Mixed Power Training Alone in Elderly Men

Université du Québec a Montréal0 个研究点目标入组 100 人开始时间: 2013年9月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
100
主要终点
Change in walking speed

研究概览

简要总结

Investigate the effect of 12 weeks mixed power training (power and functional exercises) combined with a protein supplementation (30g/d) or not (placebo) on physiological characteristics of muscle and functional capacities in elderly men.

详细描述

Life habits are know to be able to prevent the loss of functional capacities and muscle function during aging process. More specifically, protein intake is important to maintain muscle function in older adults. Another non pharmacological intervention and well recognized for its efficacy, it's exercise training.

Recently, it has been observed than muscle quality is more important to maintain physical autonomy than muscle mass per se. In addition, muscle quality is more related to functional capacities than muscle mass.

Due to this recent finding, it has been proposed that muscle power training would be the best exercise intervention to prevent the loss of mobility.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Prevention
盲法
Double (Participant, Investigator)

入排标准

年龄范围
60 Years 至 —(Adult, Older Adult)
性别
Male
接受健康志愿者

入选标准

  • Elderly men
  • 60 years and older
  • Sedentary men
  • Not obese (BMI <30 kg/m2)
  • Living in free-living community

排除标准

  • Not able to follow an exercise program (doctor authorization: XAAP)
  • Having Lactose intolerance
  • Having Pace marker
  • Having Metabolism disorder
  • No weight stable since the last 6 months
  • No stable medication (same dose and type since at least 6 months)

结局指标

主要结局

Change in walking speed

时间窗: Change from Baseline walking speed at 12 weeks measure in all subjects

evaluate using the 4m- normal walking speed (m/sec)

次要结局

  • Change in lower limb muscle quality(Change from Baseline lower limb muscle quality at 12 weeks measure in all subjects)

研究者

发起方
Université du Québec a Montréal
申办方类型
Other
责任方
Principal Investigator
主要研究者

Mylène Aubertin-Leheudre

Professor

Université du Québec a Montréal

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