Wake and Bright Light Therapy for Depression Among Admitted Patients
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- 入组人数
- 32
- 试验地点
- 1
- 主要终点
- MADRS-S score reduction of 50%
研究概览
简要总结
A randomized controlled trial comparing wake therapy (single night) followed by bright light therapy to treatment as usual.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Depressive episode requiring admission to a psychiatric hospital (including unipolar and bipolar depression).
排除标准
- •Psychotic symptoms/agitation
- •Compulsory admission
- •Confusion
- •Active substance use disorder
- •Eye disease preventing bright light therapy
研究组 & 干预措施
Chronobiological intervention
Single night's wake therapy followed by bright light therapy for a week as add-on treatment to treatment as usual.
干预措施: Bright light (Device)
Chronobiological intervention
Single night's wake therapy followed by bright light therapy for a week as add-on treatment to treatment as usual.
干预措施: Single night's wake therapy (Behavioral)
Control
Treatment as usual including a private educational meeting in sleep hygiene.
干预措施: Treatment as usual - inpatient care (Other)
Control
Treatment as usual including a private educational meeting in sleep hygiene.
干预措施: Treatment as usual - medicine (Drug)
Chronobiological intervention
Single night's wake therapy followed by bright light therapy for a week as add-on treatment to treatment as usual.
干预措施: Treatment as usual - inpatient care (Other)
Chronobiological intervention
Single night's wake therapy followed by bright light therapy for a week as add-on treatment to treatment as usual.
干预措施: Treatment as usual - medicine (Drug)
Control
Treatment as usual including a private educational meeting in sleep hygiene.
干预措施: Informative meeting (Other)
结局指标
主要结局
MADRS-S score reduction of 50%
时间窗: One week
Montgomery Asberg Depression Rating Scale
次要结局
- MADRS-S score at discharge(Participants will be followed at discharge, an expected average of 2-3 weeks)
- MADRS-S score at follow-up(10-14 weeks)
- ISI score score at discharge(Participants will be followed at discharge, an expected average of 2-3 weeks)
- ISI score score at follow-up(10-14 weeks)
- ISI score reduction of 50%(One week)
- Length of stay(The number of days between admission and discharge)
- Re-admission(10-14 weeks)
- CGI score(10-14 weeks)
- Medication use(10-14 weeks)
研究者
Steinn Steingrimsson
MD, PhD, resident in psychiatry
Sahlgrenska University Hospital, Sweden