Relationship Between Mechanical Ventilator's Modes , Intra-Abdominal Pressure, Mechanical Power and Gastric Tube Tolerance Among Mechanically Ventilated Patients.
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- intra-abdominal pressure "IAP"
研究概览
简要总结
The study aims to:
Explore the relationship between MV modes on the IA, MP and GT tolerance among mechanically ventilated patients.
详细描述
Modes of MVs by means of their differential effect on intra-thoracic pressure can have a significant influence on IAP. An ideal ventilation mode could optimize respiratory mechanics and may protect a variety of body systems functions. Among the many MV modes, SIMV, BIPAP and CPAP are the three most used modes
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •adult patients requiring MV in ICU
排除标准
- •patients with abdominal or chest trauma,
- •patients with intra abdominal pathologies,
- •patients who had received more than 10 units of red blood cells or more than 5 liters of intravenous liquids over the last 24 h,
- •patients with sepsis or hepatic, or renal dysfunction,
- •patients in positions other than supine, and
- •body mass index (BMI) ≥ 30 kg/m2.
结局指标
主要结局
intra-abdominal pressure "IAP"
时间窗: day 1
IAP will be measured through foly catheter
mechanical power
时间窗: day 1
it will be: MP (J/ min) =0.098×RR×Vt × \[Peak Pressure-(DP/2)\] measured through folly catheter
gastric tube tolerance
时间窗: day 1
The GT tolerance will be presented as yes if the patient was on GT feeding, and no, if the patient had delayed gastric emptying and converted to gastric drain
次要结局
未报告次要终点
研究者
Heba.Attia@nur.dmu.edu.eg
Faculty member " lecturer"
Damanhour University