NCT07289750尚未招募4 期
The Effect of Alogliptin Combined With Pioglitazone and Metformin Hydrochloride Tablets on Glucose and Lipid Metabolism and Islet Function in Patients With Type 2 Diabetes Mellitus Complicated With Metabolic Dysfunction-associated Fatty Liver Disease
The Fourth Affiliated Hospital of Zhejiang University School of Medicine0 个研究点目标入组 80 人开始时间: 2026年5月1日最近更新:
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 80
- 主要终点
- hemoglobin A1c
研究概览
简要总结
To compare the efficacy and safety of the combination of alogliptin and actoplus met with that of actoplus met alone in improving the glucose and lipid metabolism and pancreatic function in T2DM patients complicated with MAFLD.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Clinical diagnosis of T2DM
- •Clinical diagnosis of MAFLD
- •HbA1c: 6.5-9.5%
- •BMI: 19-35 kg/m2
- •No hypoglycemic drugs or insulin have been used within half a year
排除标准
- •Severe infections, surgeries and other emergency
- •Other types of diabetes
- •Severe cardiovascular, brain, liver and kidney disorders
- •Malignant tumor
结局指标
主要结局
hemoglobin A1c
时间窗: 6 months of treatment
次要结局
未报告次要终点
研究者
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