Duration Threstholds of Intraoperative Hypotension for Postoperative Major Adverse Events
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 37,000
- 试验地点
- 1
- 主要终点
- major adverse events
研究概览
简要总结
Intraoperative hypotension is common in non cardiac surgery. longer duration of intraoperative hypotension is related with postoperative morbidity and mortality. however, with the change of hypotension criteria, the duration threshold also change. the relationship of different hypotension criteria and its duration is unclear. This study is to explore the their relationship.
详细描述
Intraoperative hypotension is common in non cardiac surgery. longer duration of intraoperative hypotension is related with postoperative morbidity and mortality. however, with the change of hypotension criteria, the duration threshold also change. the relationship of different hypotension criteria and its duration is unclear. This study is to explore the relationship between continous difference mean blood pressure criteria and its duration thresholds for postoperative major adverse events, which include acute cardiac infarction, heart failure, cardiac death, stroke and acute kidney injury.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 100 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •adults underwent elective non-cardiac surgery
排除标准
- •cardiac surgeries; kidney surgeries; obstetric surgeries; local infiltration anesthesia; surgeries without arterial pressure monitoring; perioperative data missing; patients with more than one operation within a year
结局指标
主要结局
major adverse events
时间窗: 30 days postoperatively in hospital
including acute cardiac infarction, heart failure, cardiac death, stroke, kidney injury
次要结局
未报告次要终点
研究者
Yan Zhou, MD
Principal Investigator
Peking University First Hospital