NCT01428609已完成4 期
Blood Mercury Levels Following Retrograde Amalgam Surgeries
Masoud Saatchi2 个研究点 分布在 2 个国家目标入组 14 人开始时间: 2009年9月1日最近更新:
适应症
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 14
- 试验地点
- 2
- 主要终点
- Blood mercury concentration
研究概览
简要总结
The aim of this study is to determine the blood's mercury level of patients who had amalgam root end filling surgeries. It is to be examined if the mercury concentration in blood is elevated by using amalgam retroseal.
详细描述
- A total of 14 patients who needs surgical root canal therapy (SRCT) participated in this clinical study.
- The Isfahan University Human Subjects Review Committee approved the protocol of the study.
- All patients filled in the consent form.
- Apicoectomy with retrograde amalgam filling performed for all participant.
- Blood samples were collected in three period of time immediately before and immediately after each surgery and also one week later.
- Each time 10 ml blood was drawn from each patient.
- Analysis of total mercury in blood samples was performed using cold-vapor atomic absorption spectrometry
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •older than 18 years
- •without physician-diagnosed psychological, behavioral, neurological, immunosuppressive, or renal disorders
- •having a tooth that required apical surgery
排除标准
- •using tobacco and alcohol one week before surgery and during the study
- •dealing with mercury in their job like dentists, stonemason, mine workers
结局指标
主要结局
Blood mercury concentration
时间窗: within the 7 days after surgery
次要结局
未报告次要终点
研究者
Masoud Saatchi
Associate Professor of Endodontics
Isfahan University of Medical Sciences
研究点 (2)
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