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临床试验/NCT04670341
NCT04670341已完成不适用

Quality Improvement of Saliva by Chewing Tapioca Pearls in Bubble Tea Drinks

Gadjah Mada University2 个研究点 分布在 1 个国家目标入组 15 人开始时间: 2020年9月17日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
15
试验地点
2
主要终点
Salivary C-reactive protein (CRP) level

研究概览

简要总结

Bubble tea drinks contain tea and tapioca pearls. Chewing tapioca pearls in bubble tea drinks may increase salivary components. Because of its proteins, inorganic components, and enzymes, saliva plays an important role in the body's defense against bacteria and viruses. This study aims to analyze the effect of chewing the tapioca pearls in bubble tea drinks on salivary C-reactive protein (CRP) and calcium (Ca) levels.

详细描述

Sixty saliva samples were collected from 15 subjects. The inclusion criterion was 18-25 years of age. The exclusion criteria were receiving medication, using dentures, a history of dry mouth, smoking and systemic disease. In the first week of the experiment, subjects drank bubble tea as the intervention group. In the second week, the same subjects drank tea without pearls as the control group. Each subject drank the bubble tea for 5 minutes per day over 3 days. Saliva samples were collected on the first day before bubble tea consumption (pretest) and on the third day after tea consumption (posttest). Saliva collection was performed in the morning (09:00 a.m.-12:00 p.m.) for 1 minute. Salivary CRP levels were measured using an ELISA kit, and Ca levels were determined using a test kit.

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Crossover
主要目的
Basic Science
盲法
None

入排标准

年龄范围
18 Years 至 25 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • good Oral Hygiene Index-Simplified (OHI-S) score

排除标准

  • taking medication
  • a history of dry mouth
  • systemic disease

结局指标

主要结局

Salivary C-reactive protein (CRP) level

时间窗: 3 days

Salivary CRP level was measured on the first day before chewing tapioca peals in the bubble tea drinks and drink tea. Salivary CRP level was measured on the third day after drink bubble tea and tea without tapioca pearls

次要结局

  • Calcium (Ca) level(3 days)

研究者

发起方
Gadjah Mada University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Juni Handajani

Quality improvement of saliva by chewing tapioca pearls in bubble tea drinks

Gadjah Mada University

研究点 (2)

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