NCT02085915已完成不适用
Evaluation of the Strip PeriScreen for the Fast Diagnosis of the Spontaneous Infection of the Liquid of Ascites During the Cirrhosis
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 649
- 试验地点
- 22
- 主要终点
- Sensitivity and Specificity
研究概览
简要总结
The forecast of the spontaneous infection of the liquid of ascites (ISLA) at the cirrhotic patient is still burdened by a heavy mortality. The fast diagnosis of the ISLA is thus an essential stake to improve the forecast.
Investigators would so like to estimate the interest of the strip PeriScreen for the fast diagnosis of the ISLA at cirrhotic patients . Investigators plan to include 670 patients, what would allow to make out a will at least on ascites 2000 on about twenty centers for duration estimated of 12 months.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Male or female over 18 years
- •Presence of ascites due to cirrhosis
- •Hospitalization for a complication of cirrhosis (ascites first decompensation, gastrointestinal bleeding, encephalopathy, etc ...).
- •Hospitalization to perform a paracentesis evacuated outpatient
- •Patients on long-term antibiotic primary or secondary prophylaxis the spontaneous bacterial peritonitis and with clinical and/or biological signs that suggest spontaneous infection of ascite.
排除标准
- •Patients with ascites urgently admitted to hospital for suspected infection receiving antibiotics for more than 12 hours.
- •chylous ascites,
- •Hemorrhagic Ascites
- •Biliary Ascites (straw)
- •Ascites heterogeneous appearance
- •Ascites not related to portal hypertension (peritoneal carcinomatosis, pancreatic ascites, tuberculosis, etc ...)
- •Patient receiving imipenem IV.
- •Patients on long-term antibiotic primary or secondary prophylaxis the spontaneous bacterial peritonitis without clinical and/or biological signs that suggest spontaneous infection of ascite.
研究组 & 干预措施
strip Peri Screen
Other
干预措施: strip Peri Screen (Other)
结局指标
主要结局
Sensitivity and Specificity
时间窗: Baseline
Comparaison of Periscreen strip whith "Trace" threshold to the cytological analysis,
次要结局
未报告次要终点
研究者
研究点 (22)
Loading locations...
相似试验
已完成
不适用
Imipenem Versus Cefepime in Spontaneous Bacterial Peritonitis and to Evaluate the Risk Factors for Treatment FailureSpontaneous Bacterial PeritonitisNCT01852630Institute of Liver and Biliary Sciences, India175
撤回
不适用
The Influence of Paracentesis on Intra-abdominal Pressure and Kidney Function in Critically Ill Patients With Liver Cirrhosis and Ascites: an Observational StudyLiver CirrhosisCritically IllAscitesNCT01091233University Hospital, Ghent
已完成
4 期
Comparison of 3 Days and 7 Days Intravenous Ceftriaxone Prophylaxis for Variceal BleedingEsophageal and Gastric VaricesGastrointestinal HemorrhageNCT00838864Far Eastern Memorial Hospital79
已完成
不适用
Data Collection and Identification of Infection-responsible Bacterial Resistances in Cirrhotic PatientsCirrhosisNCT03965260Hospices Civils de Lyon71
已完成
不适用
Spectrum, Profile and Outcome of Infections in Patients With Cirrhosis and/ or Acute on Chronic Liver FailureCirrhosisChronic Liver FailureAcute Liver FailureNCT01872767Institute of Liver and Biliary Sciences, India522