NCT02310217已完成不适用
Validation of New Tools for the Assessment of Cognitive Functions and Connectivity Network in Hypertensive Patients
Neuromed IRCCS1 个研究点 分布在 1 个国家目标入组 160 人开始时间: 2015年2月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 160
- 试验地点
- 1
- 主要终点
- Cognitive abilities measured by validated neuropsychological test battery (Montreal Cognitive Assessment test, Verbal Fluency test,learning of couple words, Stroop test)
研究概览
简要总结
The relationship among hypertension, aging and cognitive decline is complex and not completely understood. Purpose of this project will be evaluating early markers of cognitive deterioration in patients with arterial hypertension. In particular, this cross-sectional observational study will be articulated in three phases:
- Neuropsychological evaluation of general cognitive abilities
- Identification and measurement of specific biomarker levels
- Correlation among hypertension, cognitive abilities and biomarkers.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 40 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Males or females diagnosed with arterial hypertension between 40 and 65 years of age;
- •Written informed consent prior to enrollment in the study.
排除标准
- •Precedent acute myocardial infarction (AMI);
- •Previous stroke and/or transient ischemic attack (TIA);
- •Previous or concomitant neurologic or psychiatric pathologies;
- •Neurologic or psychiatric pharmacological therapy.
结局指标
主要结局
Cognitive abilities measured by validated neuropsychological test battery (Montreal Cognitive Assessment test, Verbal Fluency test,learning of couple words, Stroop test)
时间窗: 18 months
次要结局
未报告次要终点
研究者
Giuseppe Lembo
MD, PhD
Neuromed IRCCS
研究点 (1)
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