Randomized Controlled Trial of the Impact of Mobile Phone Delivered Reminders and Unconditional Travel Subsidies on Measles Vaccination in Western Kenya: The Mobile and Scalable Innovations for Measles Immunization (M-SIMI) Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 537
- 主要终点
- Measles vaccination coverage
研究概览
简要总结
The overall objective is to test the impact of short message service (SMS) reminders, with or without unconditionally provided mobile-money incentives, can improve measles vaccination coverage in rural western Kenyan infants.
详细描述
Primary Objective The primary objective is to determine if text message reminders, with or without unconditionally provided incentives, can increase the proportion of children who receive measles vaccination by 15% at age ten months as compared to control arm children.
Secondary Objectives
- To conduct a secondary analysis of the primary outcome using survival analysis and time-to-immunization curves.
- To determine if there is a differential effect on measles vaccine coverage based on mobile phone ownership and distance to the clinic.
- To examine the effect of the interventions on measles coverage measured at twelve months of age.
- To examine the completeness and costs of identifying children through a CHW approach versus the standard HDSS approach.
- To evaluate the effect of the interventions on coverage of second dose of measles vaccine at 24 months. This secondary objective is contingent on receiving additional funding.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Health Services Research
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Caregiver of infant aged 6-8 months at time of enrollment
- •Self-reported resident of one of the study villages; where the definition of a resident is defined by caregiver
- •Willing to sign informed consent for the study
排除标准
- •Child of enrolled caregiver has already received one dose of measles vaccine, not including any supplemental measles vaccines
- •Caregiver plans to move away in the next 6 months
研究组 & 干预措施
Control
All enrolled caregivers will receive a congratulatory text message at enrollment which indicates who is conducting the study and which also includes a general-health related saying, "The greatest wealth is health". No additional text messages or travel subsidies will be sent to caregivers randomized to the control arm.
SMS reminder
At enrollment, participants will be told to expect 2 SMS reminders for measles vaccine; first, at 3 days before and second, on the day before the scheduled measles vaccine at 9 months of age. At most, enrolled caregivers will receive three text messages (two for the measles vaccine and one for welcoming mother to the study). Text messages will be sent in English, Kiswahili or Dholuo language, according to the mother's preference. These reminders will have information about the child's scheduled immunization date.
干预措施: SMS reminder (Behavioral)
SMS reminder + Unconditional Incentive
Participants will receive SMS reminders as described in the SMS reminder arm. Additionally, participants will be sent a 150 Kenyan Shillings (KES) incentive to the mobile phone number they provided at enrollment. The incentive will be delivered three days before the child turns nine months (i.e. sent on the same day as the first SMS reminder). Caregivers will receive the mobile-money incentive unconditionally. The intent of the incentive is to help offset the costs associated with transportation to the clinic. The transaction costs associated with mobile-money transactions will be borne by the study such that mothers will receive the full 150 KES.
干预措施: SMS reminder (Behavioral)
SMS reminder + Unconditional Incentive
Participants will receive SMS reminders as described in the SMS reminder arm. Additionally, participants will be sent a 150 Kenyan Shillings (KES) incentive to the mobile phone number they provided at enrollment. The incentive will be delivered three days before the child turns nine months (i.e. sent on the same day as the first SMS reminder). Caregivers will receive the mobile-money incentive unconditionally. The intent of the incentive is to help offset the costs associated with transportation to the clinic. The transaction costs associated with mobile-money transactions will be borne by the study such that mothers will receive the full 150 KES.
干预措施: Unconditional Incentive (Behavioral)
结局指标
主要结局
Measles vaccination coverage
时间窗: 10 months
Proportion of children receiving measles vaccination by 10 months of age by study arm
次要结局
- Proportion of children who receive measles vaccination stratified by demographic variables(10 months)
- Time to measles vaccination (in days) using Kaplan-Meier Survival Analysis(12 months)
- Measles vaccination coverage at 12 months(12 months)
- Vaccination coverage for second dose of measles vaccine at 24 months.(24 months)
研究者
Dustin Gibson
Assistant Scientist
Johns Hopkins Bloomberg School of Public Health