Cardiovascular Health Improvement Project
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 9,999
- 试验地点
- 1
- 主要终点
- Establishing a biobank of patients with Aortic Disease
研究概览
简要总结
The goal of this project is to establish a biobank of clinical information, DNA, plasma, and aortic tissue samples from patients with cardiovascular disease as well as healthy controls.
详细描述
The goal of this project is to establish a biobank of clinical information, DNA, plasma, and aortic tissue samples from patients with cardiovascular disease as well as healthy controls. The aims of the study are to collect biological specimens (blood, plasma, serum, aortic tissue) and family history; establish a biobank, establish a comprehensive database with information from consented patients, and provide researchers with high quality well annotated DNA samples with demographic and clinical information.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Any patient over the age of 18 who is able/willing to give informed consent
- •Patients <18 years of age with parental consent and assent (if assent is applicable for their age)
- •Diagnosis of:
- •aortic pathology potentially due to a known or suspected inherited condition
- •Idiopathic aortic aneurysm
- •Interesting of novel vascular pathology in the aorta or main branches
- •Family history of aortic or vascular disease
- •Other cardiovascular disease
- •Healthy controls with no apparent cardiovascular disease
排除标准
- •Not willing or able to sign the consent
结局指标
主要结局
Establishing a biobank of patients with Aortic Disease
时间窗: 40 years
Establish a biobank of blood, serum, plasma, tissue, and clinical data of patients with any form of aortic disease
次要结局
未报告次要终点
研究者
Marion Hofmann Bowman
Associate Professor of Internal Medicine
University of Michigan