The Effects of Caffeine Supplementation on Heart Rate and Heart Rate Variability at Rest and During Submaximal Exercise
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 16
- 主要终点
- Heart rate variability
研究概览
简要总结
In previous research we have shown that an acute caffeine dose of 5 mg/kg body mass reduces heart rate at rest and during low intensity exercise, with the effect dissipating as exercise intensity increases. If, as suspected, the effect at rest and at low intensities is due to an effect of caffeine on parasympathetic activity, this is likely to be reflected in an increase in heart rate variability (the beat-to-beat fluctuation in heart rate). The aim of this study is therefore to investigate the effect of caffeine on heart rate and heart rate variability at rest and during submaximal exercise.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 55 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Trained cyclists
排除标准
- •Injured or a contraindicative medical condition
研究组 & 干预措施
Caffeine
caffeine dose of 5 mg per kg of body mass administered orally via a gelatine capsule
干预措施: Caffeine (Drug)
Placebo
maltodextrin (placebo) dose of 5 mg per kg of body mass administered orally via a gelatine capsule
干预措施: Placebo (Drug)
结局指标
主要结局
Heart rate variability
时间窗: From baseline to completion, up to 31 days
Change from baseline in heart rate variability measured at rest and at five different exercise intensities (40, 50, 60, 70 and 80% percent of maximal oxygen uptake) on an electromagnetically-braked cycle ergometer
次要结局
- Heart rate(From baseline to completion, up to 31 days)