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临床试验/NCT02459873
NCT02459873已完成不适用

Modeling and Testing Change in Mental Abilities in Childhood Through Computer-based Interventions

University of Southern California2 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2015年6月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
20
试验地点
2
主要终点
Change in working memory skills assessed through Executive Function Battery and NIH ToolBox

研究概览

简要总结

Children with low executive function, working memory and attention skills in childhood not only do poorly at school, but also go on to do poorly on social, health, and financial indicators in adulthood.

The rate of executive function disorders in children is vastly underestimated at 17% , even when taking into account two of the more widely known disorders of Attention Deficit Hyperactivity Disorder (11%) and Fetal Alcohol Spectrum Disorders (6%), but children of lower socioeconomic status are especially vulnerable due to reduced resource availability.

As executive function, working memory and attention skills are central to success in later life, if children with low skills can be given targeted training to improve the skills they fall short on, there is potential to both improve their short-term academic performance, and influence long-term achievement. In fact, poor executive function skills and poor attention and working memory is a large predictor of poor performance even in typically developing children who are doing poorly academically.

Hypothesis 1. Those with lower working memory will also have lower problem solving skills and lower indices of other executive functioning skills such as reasoning/problem solving.

Hypothesis 2. Children that start with lower WM and PS will show the highest gains in training related performance, and such high gains on WM and PS will lead to better performance post-intervention compared to baseline measures of cognitive function.

Hypothesis 3: Those who make the largest gains in WM and PS with training will show more retention of training gains at 6 months compared those who show lower gains.

Aim 1. Assess working memory (WM) and processing speed (PS) skills in children and their inter-relationships with executive functioning skills Aim 2. Examine change in cognitive function in WM and PS after intensive training in WM and PS, during and immediately post-intervention Aim 3. Examine long-term retention of training effects on WM, PS, and executive functions.

The purpose of this study is to establish an effective and targeted working memory and processing speed intervention in children ages 7-10 with low to average executive function skills, by utilizing home-based computer games specifically designed to appeal to children.

Following institution approved consents, 60 low socioeconomic status children from Los Angeles will be recruited and enrolled in the study and be asked to play specific fun, but targeted cognitive computer games for 10 weeks.

The results of this pilot study will establish a protocol for feasibility of improving executive function skills in children with underdeveloped skills and inform on sufficiency of sample sizes, length of interventions, and directly impact computer-based intervention research and cost-effective techniques in children's cognitive development within the next 3-5 years.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Basic Science
盲法
Double (Participant, Investigator)

入排标准

年龄范围
84 Months 至 132 Months(Child)
性别
All
接受健康志愿者

入选标准

  • Understands and speaks English

排除标准

  • Diagnosed psychological disorder
  • Head trauma with loss of consciousness of >5 minutes

结局指标

主要结局

Change in working memory skills assessed through Executive Function Battery and NIH ToolBox

时间窗: 3 months

Children will be assessed both on Executive Function Battery and the NIH Toolbox battery to examine change in working memory skills.

Change in processing speed skills assessed through Executive Function Battery and NIH ToolBox

时间窗: 3 months

Children will be assessed both on Executive Function Battery and the NIH Toolbox battery to examine change in processing speed skills.

次要结局

  • Change in parent reported behavior as assessed through BRIEF and CBCL questionnaires(3-6 months)
  • Change in school grades in science, reading and math.(3-6 months)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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