NCT05077553已完成不适用
Lactobacillus Plantarum TCI999 in the Efficacy Verification Program of Hair and Body Health Care
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- The change of hair density
研究概览
简要总结
To assess TCI999 on hair and body health care
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy adults aged above 20 years old
排除标准
- •Subject who is not willing to participate in this study.
- •Patients with diseases of the skin, liver, kidney.
- •Subjects who have known cosmetic, drug or food allergies, difficulty in digestive tract absorption or disorder.
- •Female who is pregnant or nursing or planning to become pregnant during the course of the study.
- •The students taught by the PI.
- •Subjects who have wounds on the scalp and subjects who have used drugs to treat the scalp, received hair transplants or other scalp treatments within six months
结局指标
主要结局
The change of hair density
时间窗: Change from Baseline hair density at 12 weeks
Take a picture and observe the hair density
The change of intestinal microbiota
时间窗: Change from Baseline intestinal microbiota at 12 weeks
To evaluate the intestinal microbiota of fecal samples
The change of hair loss amount
时间窗: Change from Baseline hair loss amount at 12 weeks
Collected and measured the weight of loss hair
The change of hair follicle strength
时间窗: Change from Baseline hair follicle strength at 12 weeks
Pull up the hair of the frontal bone, temporal bone and occipital bone (approximately 60 hairs/area) to assess the number of hair loss in each area
次要结局
- The change of testosterone of blood(Change from Baseline testosterone at 12 weeks)
- The change of AR gene expression of blood(Change from Baseline AR gene expression at 12 weeks)
- The change of dihydrotestosterone of blood(Change from Baseline hair diameter at 12 weeks)
- The change of SRD5A1 gene expression of blood(Change from Baseline SRD5A1 gene expression at 12 weeks)
- The change of scalp gloss(Change from Baseline scalp gloss at 12 weeks)
- The change of scalp redness(Change from Baseline scalp redness at 12 weeks)
- The change of hair diameter(Change from Baseline hair diameter at 12 weeks)
- The change of TGF-β gene expression of blood(Change from Baseline TGF-β gene expression at 12 weeks)
- The change of scalp health(Change from Baseline scalp health at 12 weeks)
- The change of IGF-1 gene expression of blood(Change from Baseline IGF-1 gene expression at 12 weeks)
研究者
研究点 (2)
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