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临床试验/NCT03228901
NCT03228901已完成2 期

Exploring the Effects of Oxytocin on Non-verbal Communication

Yale-NUS College1 个研究点 分布在 1 个国家目标入组 104 人开始时间: 2007年1月最近更新:
适应症
干预措施
相关药物

试验速览

阶段
2 期
状态
已完成
入组人数
104
试验地点
1
主要终点
Non-verbal communication

研究概览

简要总结

In this protocol registration, the investigators plan a secondary data analysis of a dataset to explore the effects of intra-nasal oxytocin on the non-verbal expression of affiliation.

详细描述

Using Liu et al.'s (2012) dataset, the investigators seek to observe whether the administration of oxytocin modifies non-verbal communication with a stranger.

This dataset involves a conversation between two strangers that took place 45 minutes after drug administration. While Liu et al. coded the video for markers of interpersonal distance (physical distance, eye contact, conversational intimacy), the investigators seek to analyse oxytocin's effects on non-verbal communication of affiliative and sexual cues (e.g., smiles, lip puckers). Based on findings that oxytocin's effects depend on context, the investigators will explore these relationships as a function of the conversational context (where participants converse with each other using low-, medium-, and high-intimacy topics, or in an unstructured conversation).

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Factorial
主要目的
Basic Science
盲法
Triple (Participant, Investigator, Outcomes Assessor)

入排标准

性别
All
接受健康志愿者

入选标准

  • 未提供

排除标准

  • pregnant;
  • history of epilepsy, severe depression, severe anxiety, or psychosis;
  • smoking more than 15 cigarettes a day;
  • addicted to illegal substances.

研究组 & 干预措施

Oxytocin

Experimental

24IU Syntocinon, delivered in a single nose via a nasal spray

干预措施: Oxytocin (Drug)

Placebo

Placebo Comparator

Matched nasal spray

干预措施: Placebos (Drug)

结局指标

主要结局

Non-verbal communication

时间窗: Measured in the interaction which commenced 45mins after drug administration

Based on coding the video-recorded interaction between two strangers, using a coding scheme by Gonzaga et al. (for affiliative and sexual cues)

次要结局

  • Ratings of the person participants interacted with(Measured following the interaction (which commenced 45 mins after drug administration))

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Jean Liu

Assistant Professor

Yale-NUS College

研究点 (1)

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