跳至主要内容
临床试验/NCT05133375
NCT05133375已完成不适用

Comparison of Hemodynamic Changes of Tracheal Intubation With McCoy and Macintosh Laryngoscopes

CMH Jhelum2 个研究点 分布在 1 个国家目标入组 272 人开始时间: 2021年4月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
272
试验地点
2
主要终点
Effect on the pulse of intubation with Macintosh and McCoy laryngoscope

研究概览

简要总结

A total of 272 patients were randomly allocated into two groups, Patients in group A were treated with Macintosh laryngoscope and in groups B with McCoy laryngoscope was used for endotracheal intubation. Pulse and systolic blood pressure was recorded by non-invasive measures before laryngoscopy and at 30 seconds, 2 and 3minutes after intubation. All this information was recorded on a Pro forma.

详细描述

After taking approval from hospital ethical committee, 272 patients who reported to Operation Theatre of CMH, Jhelum were selected for the study. Informed consent was obtained and patient demographic information (name, age, contact) was recorded. Patients were randomly divided in two equal groups by using lottery method. GROUP A: Where Macintosh laryngoscope was used for endotracheal intubation. GROUP B: Where McCoy laryngoscope was used for endotracheal intubation.

Before reporting to Operation theatre a detailed pre anesthesia assessment was done in all patients, all necessary laboratory investigations were collected. On OT table pulse and systolic blood pressure was checked by non-invasive method. 18G cannula was passed and ECG was attached. A pillow was placed under the head to obtain classical sniffing position for intubation. All the patients were pre medicated with injection midazolam 0.08mg/kg, injection nalbuphine 0.1 mg/kg, injection dexamethasone 0.08mg/kg and injection metoclopramide 0.1 mg/kg. Pre oxygenation was done with 100% oxygen for 3 mins. Induction was done with injection propofol2 mg/kg, muscle relaxation achieved with injection atracurium 0.5mg/kg. Laryngoscopy was started after 3 minutes by a qualified anesthetist. Pulse and systolic blood pressure was recorded by non-invasive measures before laryngoscopy and at 30 seconds, 2 and 3minutes after intubation. All this information was recorded on a Proforma.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Other
盲法
None

入排标准

年龄范围
18 Years 至 70 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Both Male and Female
  • Age between 18 to 70
  • ASA I and II males and females.
  • Malampatti I and II.
  • Hemodynamically stable, no known ischemic heart disease and no history of hypertension.
  • Nil per oral for at least 6 hours.

排除标准

  • Non consenting patient.
  • ASA III, IV or V patient.
  • Malampati III or IV.
  • Cervical instability
  • Thyromental distance of less than 6cm, inter incisor distance of less than 3cm.
  • Known case of hypertension and ischemic heart disease.
  • Pregnant female.
  • Body mass index of more than
  • Patients of oropharyngeal surgery.
  • Unable to Intubate in less than 1 minute.

结局指标

主要结局

Effect on the pulse of intubation with Macintosh and McCoy laryngoscope

时间窗: After Laryngoscopy, pulse was recorded by non-invasive measures before laryngoscopy and at 30 seconds, 2 and 3 minutes after intubation.

To measure hemodynamic changes (i.e. pulse) of intubation with Macintosh and McCoy laryngoscope

Effect on the systolic blood pressure of intubation with Macintosh and McCoy laryngoscope

时间窗: After Laryngoscopy, systolic blood pressure was recorded by non-invasive measures before laryngoscopy and at 30 seconds, 2 and 3 minutes after intubation

To measure hemodynamic changes (i.e. systolic blood pressure) of intubation with Macintosh and McCoy

次要结局

未报告次要终点

研究者

发起方
CMH Jhelum
申办方类型
Other
责任方
Principal Investigator
主要研究者

M. Awais Qarni

Anesthesiologist

CMH Jhelum

研究点 (2)

Loading locations...

相似试验