NCT01917448已完成4 期
Low-dose Spinal Morphine for Post-Thoracotomy Pain After Video-Assisted Thoracoscopic Surgery: A Prospective Randomized Double-Blind Controlled Trial
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 36
- 试验地点
- 1
- 主要终点
- Total post-operative morphine requirement.
研究概览
简要总结
One-thirds of patients underwent video-assisted thorascopic surgery still have severe pain. Therefore we want to demonstrate weather 0.15 mg spinal morphine would reduce 24 hour postoperative requirement comparing to control group.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •ASA (American Society of Anesthesiologist) physical status I to III,
- •Undergoing elective video-assisted thoracoscopic surgery at Siriraj and Thammasart Hospitals
- •capable of using a patient-controlled analgesia (PCA) machine
- •understanding the numeric rating scale (NRS) score for pain assessment.
排除标准
- •history of allergy to the study drugs
- •bleeding disorder
- •infection of the back
- •refusing spinal anesthesia
- •history of cerebrovascular disease
- •using postoperative ventilator support were excluded
研究组 & 干预措施
Control
Sham Comparator
The skin will be injected with local anesthetic without spinal block
干预措施: control (Other)
Spinal morphine
Active Comparator
0.15 mg spinal morphine
干预措施: Morphine (Drug)
结局指标
主要结局
Total post-operative morphine requirement.
时间窗: 48 hours
次要结局
- Pain after surgery(48 hour)
研究者
Sirilak Suksompong
Associate Professor
Mahidol University
研究点 (1)
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