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临床试验/NCT04393402
NCT04393402已完成不适用

Lung Ultrasound Score in Covid 19 Infectious Disease in Critical Care

Centre Hospitalier Universitaire de Nice1 个研究点 分布在 1 个国家目标入组 14 人开始时间: 2020年3月20日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
14
试验地点
1
主要终点
LUS applicability with COVID 19

研究概览

简要总结

It might be necessary with Sars-Cov2 pneumopathy patient to repeat thoracic images, the tomodensitometry ones in particular. This task is difficult and nearly impossible for several reasons: respiratory and hemodynamic unstable patient, prone position and due to the high contagious nature of the disease.

The lung ultrasound is an easy tool, fast (between 5 and 10 minutes) and as a limited training.

In the context of the Sars-Cov2 epidemic, Buonsenso and al case report depict the first lung ultrasound for a Covid 19 patient.

Peng and al in Intensive Care Medicine accentuate the usefulness of this particular technic.

In the American Journal of Respiratory and Critical Care Medicine, a study has been published as a point-of-care, in which the doctors reported using the lung ultrasound with intensive and critical care patient.

In Critical Care 2016, it has been showed that ultrasound allowed with neat precisions, to predict severe ARDS patient response to the prone position, all-cause.

Another researchers team found a good correlation between lung ultrasound, the SOFA, APACHE II, CPIS score, and patient mortality.

And a new applicability in the pulmonary recruitment by PEEP titration has been presented.

The aim of this study is to evaluate the lung ultrasound in Covid19 ARDS.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 95 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Diagnosed Sars-Cov2 patient, with PCR method qualitative or quantitative as usual.
  • Intensive or critical care admission
  • ARDS with PaO2/FiO2 <300 at the admission
  • Ventilatory support or oxygen-therapy

排除标准

  • Age < 18 years-old
  • Pregnancy
  • Patient with tutor- or curatorship or in prison

结局指标

主要结局

LUS applicability with COVID 19

时间窗: 10 months

In dorsal position, or in prone position, the two hemithorax will be subdivided in 6 parts, and a score will be attributed with the following criteria : A-Lines (0 point), \> 3 B-lines (1 point), B-Lines coalscent (2 points), and pulmonary consolidation (3 points). For the echography we can use a convexe sonde, or a "cardiac" sonde.

次要结局

  • Radiographic correlation (chest Xray and tomodensitometry)(10 months)
  • LUS Mortality prediction(10 months)
  • Prediction of Prone position response(10 months)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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