Development of Three-dimensional Deep Learning for Automatic Design of Skull Implants
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 6
- 试验地点
- 1
- 主要终点
- Number of patients where there is no need to augment/fill clefts between the Patient Specific Implant (PSI) and patient´s bone
研究概览
简要总结
This project aims to develop an effective deep learning system to generate numerical implant geometry based on 3D defective skull models from CT scans. This technique is beneficial for the design of implants to repair skull defects above the Frankfort horizontal plane.
详细描述
Designing a personalized implant to restore the protective and aesthetic functions of the patient's skull is challenging. The skull defects may be caused by trauma, congenital malformation, infection, and iatrogenic treatments such as decompressive craniectomy, plastic surgery, and tumor resection. The project aims to develop a deep learning system with 3D shape reconstruction capabilities. The system will meet the requirement of designing high-resolution 3D implant numerical models efficiently.
A collection of skull images were used for training the deep learning system. Defective models in the datasets were created by numerically masking areas of intact 3D skull models. The final implant design should be verified by neurosurgeons using 3D printed models.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 15 Years 至 80 Years(Child, Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Scheduled for cranioplasty
- •Informed consent
排除标准
- •(1)No informed consent
结局指标
主要结局
Number of patients where there is no need to augment/fill clefts between the Patient Specific Implant (PSI) and patient´s bone
时间窗: 6 weeks after surgery by standardised questionnaire
Number of patients where there is no need to augment/fill clefts between the Patient Specific Implant (PSI) and patient´s bone
Number of patients where there is no need to adapt the Patient Specific Implant (PSI) edges
时间窗: 6 weeks after surgery by standardised questionnaire
Number of patients where there is no need to adapt the Patient Specific Implant (PSI) edges
次要结局
未报告次要终点
研究者
Yau-Zen Chang
Professor
Chang Gung Memorial Hospital
