NCT01891578Unknown不适用
Evaluation of Immunological Reconstitution After Haploidentical Bone Marrow Transplantation Using a Nonmyeloablative Preparative Regimen and Post-transplant Cyclophosphamide, in Patients With Poor Prognosis Lymphomas
Armando Santoro, MD1 个研究点 分布在 1 个国家目标入组 23 人开始时间: 2011年1月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 23
- 试验地点
- 1
- 主要终点
- Evaluation of T lymphocytes and NK cells absolute number
研究概览
简要总结
Evaluation of immunological reconstitution after haploidentical BMT using a nonmyeloablative preparative regimen and post-transplant cyclophosphamide in patients with poor prognosis lymphoma
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with lymphoma (any histology) relapsed after high dose chemotherapy and in partial remission, complete remission or stable disease after the last CT line that
- •Signed informed consent to perform an haploidentical allo-BMT using a nonmyeloablative preparative regimen and post-transplant cyclophosphamide
排除标准
- 未提供
结局指标
主要结局
Evaluation of T lymphocytes and NK cells absolute number
时间窗: 1 year
次要结局
- Evaluation of discrete T-cells populations(1 year)
- Evaluation of antigen-specific T cell populations(1 year)
- Evaluation of antigen-specific T lymphocyte's functionality(1 year)
- Evaluation of cytokines production by IL-2 and anti-CD16 activated NK cells(1 year)
研究者
Armando Santoro, MD
MD
Istituto Clinico Humanitas
研究点 (1)
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