Search for Biomarkers in Human Glaucoma: Possible Correlations Between Alterations in Peripheral Lymphocytes and Disease Severity

University of Parma1 个研究点分布在 1 个国家目标入组 40 人开始时间: 2007年6月最近更新: 2009年9月22日

适应症

试验速览

阶段: 不适用
状态: 已完成
发起方: University of Parma
入组人数: 40
试验地点: 1
主要终点: compare the lymphocyte phenotype of POAG patients to healthy subjects of the same age

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

The aim of this study was to evaluate the lymphocyte phenotype in primary open- angle glaucoma (POAG) patients compared to healthy subjects of the same age, in order to confirm the importance of immune responses in glaucoma and the possible correlation to the severity of the disease.

研究设计

研究类型: Observational
观察模型: Case Control
时间视角: Retrospective

入排标准

年龄范围: 19 Years 至 85 Years（Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•Clinical diagnosis of primary open-angle glaucoma
•age between 19 an 85 years old

排除标准

•age less than 19 or more than 85 yrs
•positive history for (a) neurodegenerative diseases, (b) autoimmune diseases, (c) cancer, (d) viral infection and (e) diabetes, (f)systemic inflammation

结局指标

主要结局

compare the lymphocyte phenotype of POAG patients to healthy subjects of the same age

时间窗: the same day of bloodwithdrawal

次要结局

correlate the immunophenotype of POAG patients to the severity of disease(within 3 months after blood withdrawal)

研究者

发起方

University of Parma

申办方类型

Other

研究点 (1)

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