Assessment of Coronary Artery Disease in Asymptomatic Population Undergoing Coronary Computed Tomography Angiography: A Single Center, Prospective Observational Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 6,343
- 主要终点
- The prevalence of CAD
研究概览
简要总结
A total of 9269 adults who received CCTA scans for coronary disease evaluation during a general medical checkup at the Health Screening and Promotion Center in Asan Medical Center, Seoul, Korea between January 2007 and December 2011 were initially selected. All participants were provided with information about the potential benefits and risks of CCTA and made the decision to undergo the procedure at their own expense. They were also informed that their clinical and radiological data would be used for this study and gave their consent. Of these individuals, 7129 agreed to participate, and 6343 were enrolled in this CCTA registry.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- •a previous history of angina or myocardial infarction;
- •abnormal rest electrocardiographic results, i.e., pathological Qwaves, ischemic ST segments or T wave changes, or left bundle-branch blocks;
- •insufficient medical records;
- •structural heart diseases;
- •a prior history of open heart surgery or percutaneous coronary intervention;
- •a previous cardiac procedure; or
- •renal insufficiency (creatinine N1.5 mg/dL)
结局指标
主要结局
The prevalence of CAD
时间窗: 5 years
Diameter stenosis \>50% in any coronary artery by coronary CT angiography
次要结局
- Revascularization(5 years)
- cardiovascular mortality(5 years)
- All cause mortality(5 years)
- myocardial infarction(5 years)
研究者
Seung-Whan Lee
Principal investigator, clinical professor
CardioVascular Research Foundation, Korea