NCT00733382Unknown1 期
The Effect of Dexamethasone in the Attack of Migraine Headache and to Prevent of Its Relapse After Discharge From Emergency Department: a Randomized, Double-Blind, Controlled Trial.
适应症
干预措施
相关药物
试验速览
- 阶段
- 1 期
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- to evaluate the efficacy of dexamethazone in abortive therapy of migraine attack and prevent of recurrence
研究概览
简要总结
Dexamethasone is a safe and cheap abortive therapy for migraine headache. The effect of it is never evaluate and not correlate with the effect of popular anti migraine medication such as dihydroergotamine. The investigators proposal is to compare its effect with dihydroergotamine.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- Double (Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 15 Years 至 40 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Migraine attack according to international headache society criteria
- •Migraine without aura; at least 5 attack with mean duration of 4 to 72 hours and 2 of following:
- •Unilateral
- •Pulsatile
- •Severe enough to impair daily activity
- •Aggravate with walking and climbing, also 1 of following:
- •Nausea and or vomiting
- •Photophobia and phonophobia, and not contributed to other headache.
- •Migraine with aura; at least 2 attacks with 3 of following:
- •One reversible aura
- •Aura became apparent at least in 4 minutes
- •Aura not lasting more than 60 minutes
- •Headache develops in less than 60 minutes after aura
排除标准
- •Hypertension
- •Ischemic heart disease
- •Basilar migraine with sign and symptoms such as:
- •Dysarthria
- •Dysphagia
- •Sensory disorder
- •Drowsiness
- •Peripheral vascular disease
- •Age more than 40 and less than 15 year old
- •Use of triptans and ergots derivatives in past 24 hours
研究组 & 干预措施
1
Experimental
干预措施: dexamethazone (Drug)
2
Active Comparator
干预措施: dexamethazone (Drug)
结局指标
主要结局
to evaluate the efficacy of dexamethazone in abortive therapy of migraine attack and prevent of recurrence
次要结局
未报告次要终点
研究者
研究点 (1)
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