Physiolocal Effects of 6 Months DHEA Substitutional Therapy in Female Adrenal Failure in a Randomised, Placebo Controlled and Overcrossed Study.

University of Aarhus0 个研究点目标入组 10 人开始时间: 2001年10月1日最近更新: 2007年5月10日

适应症

试验速览

阶段: 不适用
状态: 已完成
发起方: University of Aarhus
入组人数: 10
主要终点: Quality of life parameteres, cardiovascular parameters, bodycomposition, exercise parameters, hormonal and serological parameters, fuel metabolisme.

研究概览研究设计入排标准结局指标研究者记录与标识符相似试验

研究概览

简要总结

DHEA is an adrenal deriven androgen precourser. The impact of DHEA substitution therapy in adrenal failure is unknown as well as the physiologically effects of DHEA is unknown. Effects of physiologically DHEA substitution is investigated in the model of female adrenal failure.

研究设计

研究类型: Interventional
分配方式: Randomized
干预模型: Crossover
主要目的: Treatment
盲法: Double

入排标准

年龄范围: 18 Years 至 60 Years（Adult）
性别: Female
接受健康志愿者: 否

入选标准

•Adrenal insuficiency,
•Stable and safe anticonception,
•Stable hydrocortison substituation treatment.

排除标准

•Neoplastic and thromboembolic disease,
•Diabetes mellitus.

结局指标

主要结局

Quality of life parameteres, cardiovascular parameters, bodycomposition, exercise parameters, hormonal and serological parameters, fuel metabolisme.

时间窗: six months

次要结局

未报告次要终点

研究者

发起方

University of Aarhus

申办方类型

Other

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