Randomised Comparative Clinical Trial To Evaluate The Efficacy Of Punarnavadi Kwath And Varunadi Kwath In The Management Of Mutravaha Srotodushti W.S.R. Chronic Kidney Disease.
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Changes in the clinical symptoms of Mutravaha Srotodushti (Chronic Kidney Disease).
研究概览
简要总结
AIMSAND OBJECTIVES:
qTo evaluate and compare the clinicalefficacy of “Punarnavadi Kwatha†and “Varunadi Kwatha†in the management of Mutravaha Srotodushti w.s.r to Chronic Kidney Disease.
NEED OFSTUDY:
qRetarding the progression of renalfailure is one of the most important task of the nephrologist as it not onlyinvolves the quality of life of patient but also delays the development of endstage renal diseases, use of dialysis, transplantation cause financial burdento patient.
q Varunadi Kwatha seem to be helpful to relieve the Kapha and Vata Dosha and Punarnavadi Kwatha has Rasayan properties for Mutravaha Srotas which can prevent and repaired a tissuedamage.
q After reviewing the literature andkeeping in mind the Dosha- Dushya of Mutravaha Srotodusti, Punarnavadi Kwath and Varunadi Kwatha has been chosen for the study as thesedrugs possess above mentioned properties.
HYPOTHESIS:
NULLHYPOTHESIS:
There is nosignificance difference between the effect of trial drug ( PunarnavadiKwathand Varunadi Kwath)
ALTERNATIVEHYPOTHESIS:
There is a significant difference between theeffect of trial drugs (Punarnavadi Kwathand Varunadi Kwatha)in the managementof Mutravaha Srotodushti.
STUDYDRUGS
A.PunaranavadiKwath( KalpitYoga )
B.VarunadiKwath( BhavaprakashaChi.37/12 )
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Open Label
入排标准
- 年龄范围
- 21.00 Year(s) 至 59.00 Year(s)（—）
- 性别
- All
入选标准
- •1 Patient willing to participate in clinical trial 2 Patients having any clinical signs and symptoms of chronic renal failure 3 Patients with Hypertension <160/100 mm of hg 4 Patients of Serum creatinine level 1.2 to 5.0 mg/dl 5 Patients of Blood urea level 40 to 150 mg/dl.
排除标准
- •1 Age: below 21 years and above 59 years 2 Patients having other associated disease like congenital disease Myeloma, Neoplasm etc.
- •3 Patient participated in any clinical trial with in last six months.
- •4 Pregnant or lactating women.
- •5 Familial or hereditary kidney disease, e.g. Polycystic kidney.
结局指标
主要结局
Changes in the clinical symptoms of Mutravaha Srotodushti (Chronic Kidney Disease).
时间窗: 30 Days
次要结局
- Changes in the objective parameters.(30 Days)