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临床试验/NCT04016064
NCT04016064已完成不适用

Evaluation of Temperature and Healing in Treatment of Gingival Enlargement Using Different Gingivectomy Techniques

Tokat Gaziosmanpasa University1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2012年1月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
30
试验地点
1
主要终点
Epithelization

研究概览

简要总结

Aim: Gingival enlargement is a common clinical condition which requires surgical approaches to alleviating these enlargement areas. The aim of this study was to investigate epithelization, gingival temperature, inflammation and pain levels in post-operative healing process in 4 different gingivectomy techniques including Er:YAG laser, Nd:YAG laser, electrosurgery and conventional gingivectomy in treatment of chronic inflammatory gingival enlargements.

Material and Method: A split-mouth designed study was conducted on 37 systemically healthy patients consisting of 19 females and 18 males, who had gingival enlargement areas on the left and right of maxillary and mandibular anterior regions. Gingival crevicular fluid (GCF) samples were collected, clinical periodontal parameters and gingival temperature levels were recorded at baseline and in the postoperative period. The gingival temperature was measured during surgical procedures. Gingival temperature and epithelization levels in 3rd, 7th, 10th and 15th days; GCF levels in 15th, 30th, and 90th days and pain levels in 2nd and 8th hours and between 1st-7th days of post-operative healing process were evaluated.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Diagnostic
盲法
Single (Participant)

入排标准

年龄范围
18 Years 至 40 Years(Adult)
性别
All
接受健康志愿者
是

入选标准

  • •systemically healthy individuals
  • •the existence of at least 20 functioning teeth, the existence of chronic inflammatory gingival enlargement in anterior quadrants.

排除标准

  • •pregnancy/lactation
  • •drug use, previous periodontal therapy within 6 months
  • •previous antibiotic use within 6 months, smoking
  • •the existence of attachment/bone loss. .

研究组 & 干预措施

group 3

Other

Electrosurgery

干预措施: Er:YAG LASER, Nd:YAG laser, elctrosurgery, conventional surgery (Procedure)

group 1;

Other

Er:YAG laser

干预措施: Er:YAG LASER, Nd:YAG laser, elctrosurgery, conventional surgery (Procedure)

group 2

Other

Nd:YAG laser

干预措施: Er:YAG LASER, Nd:YAG laser, elctrosurgery, conventional surgery (Procedure)

结局指标

主要结局

Epithelization

时间窗: Epithelization was evaluated at postoperative 7th day

Wound surface epithelization in the healing process was evaluated with a staining solution (Mira-2-tone, GMBH \& Co., Duisburg, Germany). (O. Ozcelik et al., 2008)

次要结局

  • Gingival temperature(The gingival temperature was measured during surgical procedures)

研究者

发起方
Tokat Gaziosmanpasa University
申办方类型
Other
责任方
Principal Investigator
主要研究者

mehmet murat taskan

Assistant Professor

Tokat Gaziosmanpasa University

研究点 (1)

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