The Effects of Interrupting Prolonged Sitting With Intermittent Exercise on Postprandial Lipemia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 8
- 试验地点
- 1
- 主要终点
- Plasma Triglycerides
研究概览
简要总结
The purpose of this study is to investigate the effect of interrupting prolong sedentary behavior with interval exercise on postprandial metabolism following a high fat glucose tolerance test.
详细描述
All subjects complete two trials in a randomized crossover design, with each trial occurring over 4 days with a minimum of seven days between trials. The first two days of each trial serve as a control period allowing for familiarization and the control of physical activity and calorie consumption prior to the intervention. Following each control period, subjects then perform one of the interventions on Day 3. The interventions consist of either eight-hours of prolonged sitting, or eight hours of sitting interrupted every hour by five sprints lasting 4 seconds each using the interval exercise. On day 4, all subjects will undergo a high fat glucose tolerance test to determine the body's ability to clear triglycerides from the blood as well as insulin/glucose response and substrate oxidation. Blood samples will be assayed for the previously mentioned substances and postprandial gas collection will be analyzed via indirect calorimetry.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 40 Years(Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- •cardiovascular problems (e.g. pre-existing heart issues, coronary artery disease, hypertension, etc.)
- •respiratory problems
- •musculoskeletal problems that prevent prolonged sitting or exercise
- •susceptibility to fainting
- •Pregnancy
研究组 & 干预措施
Prolonged sitting without exercise
Subjects will be asked to undergo prolonged sitting (~14 hours) of 1 day and will not be asked to perform interval exercise.
干预措施: Prolonged sitting without exercise (Behavioral)
Prolonged sitting with interval exercise
Subjects will be asked to undergo prolonged sitting (~14 hours) of 1 day and will be asked to perform interval exercise every hour on the hour.
干预措施: Prolonged sitting with interval exercise (Behavioral)
结局指标
主要结局
Plasma Triglycerides
时间窗: 6-hours
Areas under the curve for triglyceride concentration will be calculated for hourly samples from a 6-hour lipid tolerance test
次要结局
- Plasma Glucose(6-hours)
- Plasma Insulin(6-hours)
研究者
Edward F. Coyle
Professor
University of Texas at Austin
