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临床试验/CTRI/2023/07/054805
CTRI/2023/07/054805尚未招募不适用

Effectiveness of Core Exercises On Knee Pain, Physical Function & Patient Reported Outcomes In Individuals Diagnosed With Knee Osteoarthritis - A Randomized Controlled Trial

未提供1 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2023年1月8日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
80
试验地点
1
主要终点
Stair Climb Test

研究概览

简要总结

Knee osteoarthritis (OA) is a prevalent condition that leads to chronic disability in older adults. Around 80% of people with OA over the age of 60 have restricted movement, and 25% have trouble completing daily tasks. In India, up to 20% of people who have knee pain and signs of OA document being unable to perform everyday tasks. Evidence from previous studies states that the strength of hip and core musculature has a direct effect on knee joint loading, which in turn leads to disease progression. Therefore. it is proposed that the current study examine the efficacy of targeted core-specific strengthening exercises in conjunction with a routine rehabilitation regimen for knee OA, and evaluate its effectiveness on pain, patient-reported functional outcomes, physical function tests, knee strength, core endurance and correlate its impact on cartilage health and disease severity. Patients with knee OA, who meet the inclusion criteria will be recruited and randomly allocated into intervention and control groups. Clinical assessments including outcome measures - VAS, patient-reported outcomes, physical function tests, and muscle strength will be assessed on baseline, 4 weeks, 8 weeks and 12 weeks. Diagnostic assessments including Xray and USG will be done at baseline and 12 weeks. Following 12 weeks, the effect of the intervention will be compared between groups and the results will be reported.

研究设计

研究类型
Interventional
分配方式
Computer generated randomization
盲法
Participant and Outcome Assessor Blinded

入排标准

年龄范围
40.00 Year(s) 至 80.00 Year(s)(—)
性别
All

入选标准

  • •Patients diagnosed with Kellgren Lawrence Grades 1- 3 of Knee OA.

排除标准

  • •Patients with severe knee OA, in whom knee replacement is indicated.
  • •Patients with a history of hip OA, lower limb joint replacement, inflammatory arthritis, spine surgery, lower limb surgery, or corticoid injection within the past three months.
  • •Patients with a diagnosis of knee OA whose clinical evaluation by the physical therapist at baseline was not consistent with knee OA based on age, history, and physical examination, or those with a diagnosis of other conditions such as knee sprain.

结局指标

主要结局

Stair Climb Test

时间窗: The above mentioned outcome measures will be taken at Baseline 4 weeks 8 weeks & 12 weeks

Physical Function Test KOOS

时间窗: The above mentioned outcome measures will be taken at Baseline 4 weeks 8 weeks & 12 weeks

30second sit to stand

时间窗: The above mentioned outcome measures will be taken at Baseline 4 weeks 8 weeks & 12 weeks

40 m fast-paced walking test

时间窗: The above mentioned outcome measures will be taken at Baseline 4 weeks 8 weeks & 12 weeks

Visual Analog Scale

时间窗: The above mentioned outcome measures will be taken at Baseline 4 weeks 8 weeks & 12 weeks

Timed Up & Go Test

时间窗: The above mentioned outcome measures will be taken at Baseline 4 weeks 8 weeks & 12 weeks

次要结局

  • Muscle strength, X-ray , USG(Baseline, 12 weeks)

研究者

发起方
未提供

研究点 (1)

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