NCT04208334已完成2 期
A Double-blind, Placebo-controlled Randomized Trial Phase II Evaluating the Effect of Curcumin for Treatment of Cancer Anorexia-Cachexia Syndrome in Patients With Stage III-IV of Head and Neck Cancer
Phramongkutklao College of Medicine and Hospital2 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2020年2月13日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- Muscle mass
研究概览
简要总结
A study of Curcumin to prevent cancer anorexia and cachexia Syndrom in locally advance and advance stage head and neck cancer (stage III, IV)
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Head and neck cancer stage III-IV
- •Cancer anorexia cachexia syndrome by 2011 Cancer cachexia an International Consensus
- •Enteral feeding with Nasogastric Tube or Gastrostomy
- •Normal Bone marrow, kidneys, and liver function
- •Normal function of enteral digestion and absorption
排除标准
- •Pregnancy
- •History of allergy to Curcumin or herbal medicine
- •History of Herbal medicine used
- •History of Billiary of obstruction
- •History of Antiplatelete or anticoagulant.
结局指标
主要结局
Muscle mass
时间窗: 60 days after intervention
We measure muscle mass by Bioelectrical Impedance Analysis (BIA)
次要结局
- BMI(60 days after intervention)
- Hand grips muscle strength(60 days after intervention)
- serum NF-kB level(60 days after intervention)
研究者
研究点 (2)
Loading locations...
相似试验
进行中（未招募）
2 期
Curcumin in Preventing Gastric Cancer in Patients With Chronic Atrophic Gastritis or Gastric Intestinal MetaplasiaGastric CarcinomaChronic Atrophic GastritisNCT02782949National Cancer Institute (NCI)50
招募中
3 期
Trial of Curcumin to Prevent Progression of Low-risk Prostate Cancer Under Active SurveillanceProstate CancerNCT03769766University of Texas Southwestern Medical Center291
已完成
2 期
Placebo Controlled, Randomized Safety and Efficacy Study of RC-1291 in Cancer Anorexia/Cachexia.Cancer CachexiaNCT00267358Helsinn Therapeutics (U.S.), Inc
已完成
2 期
Comparison Between Mirtazapine and Megestrol for the Control of Anorexia-cachexia in Cancer Patients in Palliative Care.Cancer CachexiaAnorexiaNCT03283488University of Sao Paulo52
已完成
不适用
Effect of Curcumin as Nutraceutical in Patients of DepressionMajor Depressive DisorderNCT01022632Government Medical College, Bhavnagar60