NCT04650139招募中不适用
Coronary Interventions Ulm - Coronary Chronic Total Occlusions
University Hospital Ulm1 个研究点 分布在 1 个国家目标入组 500 人开始时间: 2014年1月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 500
- 试验地点
- 1
- 主要终点
- MACE
研究概览
简要总结
The aim of the proposed project is to provide the long-term results after a recanalization attempt of chronically occluded coronary arteries.
To investigate recanalization attempt of chronically occluded coronary arteries at the Ulm University Hospital. As shown, it is known that successful recanalization of a chronic occlusion is associated with a lower event rate (reduced mortality and the need for operative myocardial revascularization) compared to unsuccessful recanalization (drug therapy). The standard in the therapy of successfully recanalized chronic occlusions is the use of drug-releasing vascular supports.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients over 18 years
- •Coronary intervention in chronic coronary artery occlusion
- •Occlusion > 3 months
- •Indication for PTCA or recanalization according to guidlines
- •Symptoms of the patient
- •Evidence of myocardial ischemia (stress ECG, scintigraphic
- •Methods, magnetic resonance imaging, stress echocardiography)
- •pathological intracoronary flow reserve, prognostic
排除标准
- •No chronic occlusion,
- •Contraindication to anti-platelet therapy
- •Acetylsalicylic acid plus clopidogrel for at least 3 months such as e.g.
- •with florid gastrointestinal ulcer disease,
- •History of hemorrhagic stroke
- •or urgent non-postponable surgical intervention.
- •Basic disease with a life expectancy of less than 12 months (here as a rule
- •no indication for PTCA or reopening available)
结局指标
主要结局
MACE
时间窗: 1 year
major adverse cardiac event
次要结局
- TLR(1 year)
研究者
Bruno Correia
Investigator
University Hospital Ulm
研究点 (1)
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