Role of Neuromuscular blocking agent Vecuronium in improving the first pass success of intubation in Pediatric Emergency An open label Randomised Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- To assess the Role of Neuromuscular Blocking Agent, Vecuronium in improving the first pass success of intubation in Pediatric emergency
研究概览
简要总结
The use of a neuromuscular-blocking during intubation can improve the quality as well as the success rate of tracheal intubation, better hemodynamic stability during induction of anesthesia, lower prevalence of hypoxemia and procedure-related complications
Usage of NMBA was also associated with reduced complications and respiratory arrest or cardiovascular collapse
Studies have shown to improve the odds of improving FPS at intubation with usage of NMBA and better ease of intubation with usage of NMBA in adults and children
However there is no consensus existing regarding the use of NMBA in children so far. Hence we have planned this study to assess the first pass success with NMBA and associated factors which will ease the intubation in children
METHODS OF THE STUDY Children of age group between 1 month to 14 years presenting to Paediatric emergency planned for intubation will be enrolled in the study and they will be allocated to the two groups by computer generated block random allocation after child satisfies the inclusion criteria
STUDY GROUP AIntubation will be done with sedoanalgesics and NMBA Vecuronium
STUDY GROUP BIntubation without NMBA Intubation will be with induction agents as per standard guidelines with sedative and analgesics
EXPECTED DURATION OF THE STUDY is18 months
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 1.00 Day(s) 至 14.00 Year(s)（—）
- 性别
- All
入选标准
- •Children of age group between 1month to 14 years presenting to Paediatric emergency planned for intubation.
排除标准
- •Anticipated Difficult airway (anatomical)
- •Syndromic children
- •Children with neuromuscular disorders
- •Children with crush injuries
- •History of anaphylaxis to any NMBA.
结局指标
主要结局
To assess the Role of Neuromuscular Blocking Agent, Vecuronium in improving the first pass success of intubation in Pediatric emergency
时间窗: Baseline during intubation
次要结局
- 1To compare the ease of ventilation at intubation with without NMBA using a validated score Vibymogensen score(2 To compare the number of intubation attempts with & without NMBA including first pass success)
研究者
Asha Jyothi Penugonda
AIIMS, Raipur