NCT03577327招募中不适用
The Gut and Skin Microbiome in Vitiligo Disease Progression
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 100
- 试验地点
- 2
- 主要终点
- Microbiome composition
研究概览
简要总结
Investigators plan to perform a pilot study that aims to characterize the microbiome of human vitiligo patients with both active and stable disease and compare this to the microbiome of age and sex matched controls. The investigators aim to answer the question whether the gut and skin microbiome of patients with vitiligo differs from the general population.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 89 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients with and/or without vitiligo lesional expansion over the past year.
- •Age/sex-matched controls who do not have a diagnosis of vitiligo
- •Subjects who are age 18-89 years of age at time of enrollment
- •Subjects who are able and willing to give informed consent for this study and the Dermatology Tissue Acquisition and Biorepository (STU00009443)
排除标准
- •Subjects who are younger than 18 years of age or 90 years of age or older
- •Subjects who are unable to give consent
结局指标
主要结局
Microbiome composition
时间窗: 12 months
Diversity analysis of microbiome samples in control subjects versus vitiligo subjects (measured by number of bacteria species/sample)
Disease Progression
时间窗: 12 months
Disease progression in control subjects versus vitiligo subjects (measured by VASI score (0-100)).
次要结局
- Diet History Food Frequencies(12 months)
研究者
I Caroline Le Poole
Professor
Northwestern University
研究点 (2)
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