NL-OMON30092尚未招募不适用
Pharmacogenetic testing in the clinical setting: is screening for TPMT genotype a cost-effective treatment strategy? The first prospective randomized controlled trial within the Dutch health care system. - cost-effectiveness of TPMT pharmacogenetic testing
Zorgonderzoek Nederland (ZON)0 个研究点目标入组 1,000 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 1,000
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •· Age 18 or older
- •· Diagnosis of a form of IBD
- •· Patient is started on azathioprine treatment
- •· Patient giving informed consent
排除标准
- •· Previous treatment with azathioprine
- •· Co-prescription of allopurinol (this treatment blocks xanthine oxidase, an enzyme
- •important for azathioprine metabolism)
- •· Baseline leukocyte count less then 3x10^9 per litre
- •· Reduced baseline liver function
- •· Reduced renal function at baseline
- •· Use of TPMT phenotype test to guide prescription
- •· Pregnancy or breastfeeding
研究者
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