Intrapartum Hydration
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- Length of time from enrollment until delivery
研究概览
简要总结
The purpose of this study is to determine that maternal hydration during labor with fluids containing glucose at a rate of 125 ml per hour does not affect the duration of labor compared to Ringer Lactate at a rate of 250 ml per hour.
详细描述
During labor it is a common practice that the parturient is fastening and having fluid replacement through intravenous hydration (IVH), the rational being to avoid aspiration of gastric content in a situation of need for urgent intervention and general anesthesia with tracheal intubation. It is acceptable to infuse 125 ml per hour of a physiological solution that does not contain sugar, but the volume is not adjusted to the weight of mother, the level of effort or relaxation she is experiencing and it may well be below the required amount. From studies in the field of sport medicine it is clear that the amount of fluid reaching the muscle has an impact on the efficiency of the muscle at the level of tissue and the level of personal achievement in sports. Only few studies dealt with the amount and contents of IVH during labor that will be sufficient and meet all physiologic requirements of the parturient and her fetus.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Nulliparous women
- •Gestational age 37-41 weeks
- •Cervical dilatation 1-3 cm
- •Vertex presentation
- •Singleton
排除标准
- •Preeclampsia
- •Intra uterine fetal growth restriction
- •Duration of labor less than an hour
- •Maternal chronic disease
- •Maternal fever upon admission.
结局指标
主要结局
Length of time from enrollment until delivery
时间窗: within the first 48 hours after delivery
次要结局
- Mode of delivery(within the first 48 hours after delivery)
- Neonatal outcome(within the first 48 hours after delivery)
研究者
Raed Salim
MD
HaEmek Medical Center, Israel