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临床试验/NCT00780364
NCT00780364终止不适用

Sour Taste and Cold Temperature Effects on Pharyngeal Transit Time After Ischemic Stroke:Anatomic and Functional Bases.

UPECLIN HC FM Botucatu Unesp1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2008年3月最近更新:
适应症

试验速览

阶段
不适用
状态
终止
发起方
入组人数
30
试验地点
1
主要终点
Sour Taste and Cold Temperature in Dysphagia

研究概览

简要总结

The objective is to establish the effect of sour taste and cold temperature on the pharyngeal swallowing transit time after ischemic hemisphere stroke.

详细描述

Over the past decade there were many studies over normal and pathological swallowing that discuss the influence of taste and temperature. Nevertheless there were many questions on the issue that remains to be solved, including the hemispheric lateralization of lesions dysphagic patients remains also to be fully understood.Swallowing disorder is defined as oropharyngeal dysphagia in presence of alterations in any phase of the complex swallowing dynamics. It could be congenital or acquired, affecting nutritional aspects, hydration, lung function and the individual's social integration [1]. Stroke, has a high incidence among neurological diseases, and cause disturbs on swallowing dynamics presenting signs of dysphagia in at least 50% of cases.A study that analyzed swallowing dynamics by videofluoroscopy in individuals with history of one or more stroke episodes with oropharyngeal dysphagia shows shorter pharyngeal and oropharyngeal transit times with cold stimulus than without them. Other study of heterogeneous neurological diseases such as cerebral palsy, brain trauma, stroke, and Alzheimer's disease, concluded that sour taste improved swallowing, minimizing laryngotracheal penetration and aspiration in individuals with neurological damaged. Chen et al. in an analysis of 42 healthy individuals with several taste bolus found that awareness and arousal could also influence the swallowing function.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
50 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •Clinical diagnosis of stroke

排除标准

  • •instability clinic

结局指标

主要结局

Sour Taste and Cold Temperature in Dysphagia

时间窗: 24 months

次要结局

未报告次要终点

研究者

发起方
UPECLIN HC FM Botucatu Unesp
申办方类型
Other
责任方
Principal Investigator
主要研究者

Paula Cristina Cola

PhD

UPECLIN HC FM Botucatu Unesp

研究点 (1)

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Sour Taste and Cold Temperature in Dysphagia | 临床试验