A Comparative Study of Vaginal Misoprostol Two Dosing Regimen for First Trimester Pregnancy Termination in Patients Admitted at Bandarabbas in Shariati Hospital in 2009
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 41
- 试验地点
- 1
- 主要终点
- Abortion
研究概览
简要总结
The aim of this study is to compare two misoprostol regimen in pregnancy termination.
详细描述
Studies on determining the optimal dosage for misoprostol in pregnancy termination are continuing and still there is no evidence for ideal misoprostol regimen for pregnancy termination. The aim of this study is to compare two misoprostol regimen in pregnancy termination.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •All women who were candidates for early pregnancy termination because of fetal death or other medical conditions
- •Before 14th week of gestation calculated according LMP or first trimester sonography
排除标准
- •Chorioamnionitis
- •Hypersensitivity to prosstaglandins
- •Past medical history of cardiovascular, kidney or liver or lung diseases
- •Positive history for uterus pathologies
- •suspicious to extra-uterus pregnancy
- •sign and symptoms of uterus infection
- •Molar pregnancy
研究组 & 干预措施
400 microgram misoprostol
400 micrograms misoprostol each 6 hours for 8 dose
干预措施: Misoprostol 400 micrograms (Drug)
800 micrograms misoprostol
800 micrograms misoprostol each 12 hours for 4 dose
干预措施: Misoprostol 800 micrograms (Drug)
结局指标
主要结局
Abortion
时间窗: 48 hours after treatment
After 48 hours after treatment each patient is assessed for abortion. Patients are devided into three groups including complete, partial or no abortion.
次要结局
- Duration of abortion(Form the begining of treatment to complete abortion)
- Adverse Effects(48 hours after treatment)
- Need for surgery(48 hours after treatment)
研究者
Hamidreza Mahboobi
Medical Doctor
Hormozgan University of Medical Sciences