Estimation of Salivary Lactoferrin in Chronic Periodontitis Associated with Type -2 Diabetes Mellitus. A Clinico-biochemical Study.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 51
- 试验地点
- 1
- 主要终点
- Plaque Index,Modified Sulcular Bleeding Index, Probing Depth, Clinical Attachment Loss.
研究概览
简要总结
All the patients were explained about the aim, nature and design of the study along with a written Informed Consent for their participation before the Commencement of the study. A Clinico- Biochemical Study was Conducted by the Department of Periodontology, Narayana Dental College and Hospital, Nellore,Andhra Pradesh, India. To correlate the Salivary Lactoferrin levels in Diabetes Mellitus and chronic Periodontitis before and after Periodontal Phase- I Treatment. Patients with age limit 30-50 years will be selected from the out patient Department of Periodontology. Subjects were divided into 3 groups.Group-1 periodontally healthy subjects, Group-2 chronic periodontitis patients, Group-3 chronic periodontitis with diabetes mellitus patients.clinical parameters such as plaque index, bleeding index, probing depth, clinical attachment levels are recorded using periodontal probe before saliva sample collection.Unstimulated saliva was collected from the three groups and will be subjected to analysis of Lactoferrin levels. Group- 2 and Group-3 are subjected to phase I periodontal treatment and recordings are performed at baseline and after 4 weeks. values recorded are subjected for statistical analysis. Results are yet to come.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 30.00 Year(s) 至 50.00 Year(s)(—)
- 性别
- All
入选标准
- •Age greater than 30yrs 2)greater than 20 teeth present 3)greater than 10% of teeth with probing depth of greater than or equal to 4mm 4)Bleeding on probing.
排除标准
- •No other systemic disease apart from diabetes 2)Smokers 3)Patients who had received periodontal therapy with in 6months before study.
结局指标
主要结局
Plaque Index,Modified Sulcular Bleeding Index, Probing Depth, Clinical Attachment Loss.
时间窗: Baseline and 1 month after Phase - I Periodontal Therapy
次要结局
未报告次要终点
