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临床试验/CTRI/2017/11/010333
CTRI/2017/11/010333已完成不适用

Estimation of Salivary Lactoferrin in Chronic Periodontitis Associated with Type -2 Diabetes Mellitus. A Clinico-biochemical Study.

D Anusha1 个研究点 分布在 1 个国家目标入组 51 人开始时间: 2016年2月16日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
51
试验地点
1
主要终点
Plaque Index,Modified Sulcular Bleeding Index, Probing Depth, Clinical Attachment Loss.

研究概览

简要总结

All the patients were explained about the aim, nature and design  of the study along with a written Informed  Consent for their participation  before the  Commencement of the study. A Clinico- Biochemical Study was Conducted by the Department of Periodontology, Narayana Dental College and Hospital, Nellore,Andhra Pradesh, India. To correlate the Salivary Lactoferrin levels in Diabetes Mellitus and chronic Periodontitis before and after Periodontal  Phase- I Treatment. Patients with age limit 30-50 years will be selected from the out patient Department of Periodontology. Subjects were divided into 3 groups.Group-1 periodontally healthy subjects, Group-2   chronic periodontitis patients, Group-3 chronic  periodontitis with diabetes mellitus patients.clinical parameters such as plaque index, bleeding index, probing depth, clinical attachment levels are recorded  using periodontal probe before saliva sample collection.Unstimulated saliva was collected from the three groups and will be subjected to analysis of Lactoferrin levels. Group- 2 and Group-3 are subjected  to phase I periodontal treatment  and recordings are performed at  baseline and  after  4 weeks. values  recorded  are subjected for statistical analysis. Results are yet to come.

研究设计

研究类型
Interventional
分配方式
Computer generated randomization
盲法
Participant and Outcome Assessor Blinded

入排标准

年龄范围
30.00 Year(s) 至 50.00 Year(s)(—)
性别
All

入选标准

  • •Age greater than 30yrs 2)greater than 20 teeth present 3)greater than 10% of teeth with probing depth of greater than or equal to 4mm 4)Bleeding on probing.

排除标准

  • •No other systemic disease apart from diabetes 2)Smokers 3)Patients who had received periodontal therapy with in 6months before study.

结局指标

主要结局

Plaque Index,Modified Sulcular Bleeding Index, Probing Depth, Clinical Attachment Loss.

时间窗: Baseline and 1 month after Phase - I Periodontal Therapy

次要结局

未报告次要终点

研究者

发起方
D Anusha
申办方类型
Other [self ]

研究点 (1)

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