NCT01460433已完成不适用
A Compartmental Analysis of HIV Reservoirs and Immune Reconstitution (C)
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 21
- 试验地点
- 1
- 主要终点
- Herpes Simplex Virus - Type 2 shed rate
研究概览
简要总结
The aim of this study is to find out if the process of HIV replication in the lymph tissue and gut tissue of people taking HIV drugs causes long-term damage to the ability of the gut to protect you from other infections and health problems.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •HIV+ individuals
- •Seropositive for HIV
- •On ART for at least 12 months
- •Seropositive for Herpes Simplex Type 2 and Cytomegalovirus
- •Age ≥ 18 years
- •Negative pregnancy test for eligible women of childbearing potential
- •HIV- individuals
- •Seronegative for HIV
- •Seropositive for Herpes Simplex Type 2 and Cytomegalovirus
- •Age ≥ 18 years
- •Negative pregnancy test for eligible women of childbearing potential
排除标准
- •Taking daily suppressive therapy for Herpes Simplex Type 2
- •Contraindication to surgical & endoscopic procedures (as judged by PI)
- •Psychiatric or psychological illness that would make adherence to protocol procedures unlikely
- •Pregnancy
结局指标
主要结局
Herpes Simplex Virus - Type 2 shed rate
时间窗: 60 days
次要结局
- Evidence of HIV replication in blood and lymphoid tissue(60 days)
研究者
研究点 (1)
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