Analysis of Biomarkers From Patients With Chorioretinal Diseases
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Biomarkers in ocular fluids
研究概览
简要总结
This study was conducted to investigate the levels of ocular biomarkers from the patients with chorioretinal diseases including diabetic retinopathy, retinal vascular diseases, age-related macular degeneration (dry and wet), and retinal degeneration.
详细描述
This prospective, case-control study included 50 patients(50eyes) with chorioretinal diseases including diabetic retinopathy, retinal vascular diseases, age-related macular degeneration (dry and wet), and retinal degeneration. and 50 patient with nondiabetic retinopathy or cataract. Ocular fluids and blood samples were taken before injection of anti-vascular endothelial growth factor agent or pars plana vitrectomy for other retinal disease. Ocular biomarkers were analyzed.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •age over 20 years
- •patients requiring ophthalmologic treatments for different degrees of decreasing of visual acuity.
- •patients with chorioretinal diseases including diabetic retinopathy, retinal vascular diseases, age-related macular degeneration (dry and wet), and retinal degeneration.
- •control patients asking cataract surgery or vitrectomy for posterior segment nonproliferative disorders.
排除标准
- •under the age of 20 years
- •patients that received any anti-vascular endothelial growth factor agent for proliferative disease before taking sample of aqueous humor
- •patients that did not signed the informed consent of the trial
- •patients with intraocular inflammations or infections that requiring any pharmaceutical agent
- •patients with recent ocular trauma
研究组 & 干预措施
Chorioretinal diseases
chorioretinal diseases including diabetic retinopathy, retinal vascular diseases, age-related macular degeneration (dry and wet), and retinal degeneration.
干预措施: Chorioretinal diseases (Drug)
结局指标
主要结局
Biomarkers in ocular fluids
时间窗: one month
To establish if certain type of chorioretinal diseases group are associated to different concentrations of gene or protein concentration.
次要结局
未报告次要终点
研究者
Dong Ho Park
Department of Opthalmology, School of medicine, Kyungpook National University
Kyungpook National University Hospital