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临床试验/NCT06501729
NCT06501729已完成不适用

Potential Effect of Oral Kissing Between Two People Against the Decrease in pH

Universidad Catolica Santiago de Guayaquil2 个研究点 分布在 1 个国家目标入组 33 人开始时间: 2024年7月30日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
33
试验地点
2
主要终点
salivary pH

研究概览

简要总结

The pH of saliva can be acidic or alkaline; When it is acidic, the tooth enamel is demineralized, that is, weakened. Additionally, bacteria in the mouth can increase and cause infections such as cavities. This occurs when we consume sugary or fermented drinks, such as soda or beer.

The intention of the research team is to give some of these drinks to the study participants and verify the decrease in salivary pH. Next, a group of people will be asked to kiss their partner on the mouth, and then the pH will be measured again to see if it increases, that is, if it stops being acidic faster than in the group that did not kiss.

The aim is to demonstrate that kissing on the mouth between two people can protect teeth from cavities by rapidly increasing the pH of saliva after it has decreased to become acidic.

详细描述

The goal of this intervention study will be to determine if oral kissing between two people can increase salivary pH more quickly after drinking artificial juices, soft drinks, or (non-alcoholic) beers. It will also be studied whether the pH restoration time is faster when only one person kisses one of the named drinks or when both people do it. The main questions that are intended to be answered are the following:

  • Is the act of kissing on the mouth capable of increasing the pH of saliva more quickly than physiologically after consuming a sugary or fermented drink that has decreased it?
  • Is the increase in salivary pH after an oral kiss more accelerated when only one person consumes sugary or fermented drinks than when both people do so? The investigators will measure the basal pH of all participants before providing them with one of the drinks (artificial fruit juice, soda, or non-alcoholic beer). The researchers will then give the drinks and measure the decrease in salivary pH in all groups. Control group participants will not kiss; They will only wait for the salivary pH to neutralize physiologically. The rest of the couples will be divided into two groups: the group in which only one person in the couple consumes the sugary or fermented drink, and the group in which both people in the couple do so.

Saliva pH measurements will be performed, after initiation and consumption of the drinks, every 5 minutes for up to 40 minutes. That is, until the restoration of salivary pH is ensured in all groups.

Participants:

  • They will be between 18 and 30 years old to reduce the probability of consuming medications that alter salivary pH.
  • They should not be taking medications that alter the pH of saliva.
  • They must be in good health.
  • They should not have abscesses in the oral cavity.
  • They must have good oral health according to the loss proposed and the observed index.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Prevention
盲法
None (Participant)

入排标准

年龄范围
18 Years 至 30 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • They must be in good health
  • They must have good oral health according to the raised loss and observed index.
  • They will be between 18 and 30 years old to reduce the probability of consuming medications that alter salivary pH.

排除标准

  • Be taking medications that alter the pH of saliva.
  • Have abscesses in the oral cavity

研究组 & 干预措施

Control

No Intervention

The couples in the control group will not kiss; they will only wait for the salivary pH to neutralize physiologically.

Only one person consumes the drink

Experimental

the group in which only one person in the couple consumes the sugary or fermented drink and they kiss

干预措施: Kiss (Other)

Both people consume the drink

Experimental

In this group, both people will consume the drinks and then kiss.

干预措施: Kiss (Other)

结局指标

主要结局

salivary pH

时间窗: In a period of every 5 minutes, until reaching 40 minutes, which is the time in which physiologically the pH of the saliva is neutralized.

It is expected to measure the progressive increase in pH until reaching a neutral point, which occurs physiologically between 30 to 40 minutes, and compare the time spent by the control group with that of the experimental group. Measurements will be taken every 5 minutes from the kiss, which will last 40 seconds. In total, there will be 8 measurements, not counting the initial one for surveying the baseline. The measurement will be carried out with a calibrated pH meter. People will be asked to drool into a test tube

次要结局

未报告次要终点

研究者

发起方
Universidad Catolica Santiago de Guayaquil
申办方类型
Other
责任方
Principal Investigator
主要研究者

Fernando Armijos Briones

Teaching researcher

Universidad Catolica Santiago de Guayaquil

研究点 (2)

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