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临床试验/CTRI/2018/01/011319
CTRI/2018/01/011319尚未招募2 期

Comparison of regimens of dexamethasone in tubercular meningitis-A randomized control trial.

All India Institute of Medical Sciences0 个研究点目标入组 0 人开始时间: 待定最近更新:

试验速览

阶段
2 期
状态
尚未招募

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

入选标准

  • 1. Age 12 years or above
  • 2. Clinical evidence of Tubercular meningitis(TBM) in the form of fever and headache >14 days with/without vomiting or impaired consciousness along with one sign of meningeal irritation.
  • 3. Along with the clinical criteria any one of the following:
  • a. CSF evidence of lymphocytic pleocytosis( >20 TLC with >60% lymphocytes) and low sugar( <60 mg%) with high protein ( >100 mg%)
  • b. Radiological involvement- 2 or more of the following- Basal exudates,hydrocephalous, infarcts or gyral enhancement.
  • c. Extraneural TB- active tuberculosis involving lung, GI Tract, lymph nodes, skeletal and skin
  • 3. Signed and informed consent.

排除标准

  • a. Alternative diagnosis (non TB infection, malignancy on basis of CSF or imaging)
  • b. Contraindications to steroids or anti-tubercular treatment(Liver disease, history of GI bleed, duodenal ulcer or malignant hypertension or pregnant women)

研究者

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