Standardized Prenatal Management and Perinatal Outcome of Complicated Monochorionic Pregnancies
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 1,200
- 试验地点
- 1
- 主要终点
- Number of participants with Preterm Delivery
研究概览
简要总结
The purpose of this study is to collect and analyze data regarding natural history, indications for fetal interventions, and maternal and fetal/neonatal outcomes associated with complicated monochorionic twin pregnancy.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •The study population will consist of MC pregnancies (maternal, fetal, and neonatal data) that have undergone evaluation and/or treatment for complications attributable to monochorionic twin pregnancy at the University of Miami.
- •Maternal age 18 years and older.
排除标准
- •Participation declined or consent not granted in prospective arm
- •Loss to follow-up
研究组 & 干预措施
Monochorionic Pregnancy Group
Participants with complicated monochorionic pregnancies (MC) will be followed prospectively beginning at the time of the mother's evaluation for a complication related to monochorionic (MC) multiple pregnancies through delivery of the child and follow-up of the child to 12 months of life.
结局指标
主要结局
Number of participants with Preterm Delivery
时间窗: Up to 42 weeks gestation
Preterm delivery is defined as birth \<37 weeks gestation
Number of participant with Premature Spontaneous Rupture of the Membranes
时间窗: Up to 42 weeks
As per clinical evaluation
Number of Infant Deaths
时间窗: Up to 12 months post infant delivery
The Number of Infant Deaths
次要结局
未报告次要终点
研究者
Rodrigo Ruano
Professor and Chief of MFM Division
University of Miami