A pragmatic cluster randomised trial in English secondary schools comparing the impact of a policy of weekly testing for COVID-19 followed by isolation of cases and their contacts, with a policy of weekly testing followed by isolation of cases and daily testing of contacts

Department of Health and Social Care0 个研究点目标入组 200 人开始时间: 2021年5月4日最近更新: 2022年9月5日

适应症

试验速览

2021 Results article in https://pubmed.ncbi.nlm.nih.gov/34534517/ (added 21/09/2021)

•1. Secondary school/further education college
•2. Willing and able to follow the study protocol
•3. Willing and able to undertake PCR testing of contacts in the event the school is allocated to the control group
•4. Commits to maintaining contact management in line with national standards
•5. Willing and able to provide regular data of test results to Test and Trace and to allow members of an index case’s contact group to be flagged in a database.
•6. Willing and able to support baseline data collection requirements (e.g., provision of school register, bubble allocation data, etc.)
•7. Willing to communicate regularly to Participants via Participant Information Sheets and other communication materials
•8. Willing and able to provide a dedicated DHSC-funded Research Assistant to support data collection
•Inclusion criteria for DCT (in the intervention arm):
•Staff (including temporary or contract staff) and students in secondary schools/further education colleges/year 7 and above in all-through schools’ individuals, who are:
•1. Contact of a positive case related to school
•2. Asymptomatic
•3. Onsite i.e. not self-isolating or shielding
•4. Contact of an index case in the school’s population i.e. a staff member or student who has tested positive

•1. The school’s contact management policy does not conform to national standards
•2. Inability to support in-school LFD testing (i.e. not part of the NHS Test and Trace Asymptomatic Testing Site network)
•Exclusion criteria for DCT (in the intervention arm):
•1. Contact of a non-school index case
•2. Household contact of a diagnosed COVID-19 positive individual
•3. Symptomatic individuals

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