The Determination of the Effect of Norepinephrine Infusion on the Development of Pressure Injury Among Critically Ill Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 289
- 试验地点
- 1
- 主要终点
- development of pressure injury after admission to intensive care unit until discharge
研究概览
简要总结
Norepinephrine mainly increases mean arterial pressure among intensive care patients. It may be an essential risk factor in developing pressure injuries. However, there are still conflicting findings in the literature.
This study aimed to examine the effect of norepinephrine infusion on the development of pressure injuries among patients in adult intensive care.
This retrospective and correlational study was conducted between March 2021- May 2022. The electronic patient data were obtained from 289 adult patients (Case group n=149; control group n=149) treated with and without norepinephrine in the intensive care unit, respectively. The demographic and clinical characteristics were evaluated using descriptive statistical methods (number, percentage, mean, standard deviation). A logistic regression model was established to estimate the dependent variable (development of pressure injury) with the independent variables.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •The sample consisted of all patients
- •over 18 years old
- •who did not have pressure injuries upon admission to the intensive care unit. Patients who received norepinephrine and received norepinephrine infusion for at least 48 hours during their stay in ICU were included in the case group (n=149), and patients who did not receive an infusion were included in the control group (n=140).
排除标准
- •The sample excluded of all patients
- •less than 18
- •who have pressure injuries during admission
- •who had norepinephrine infusion less than48 hours during their stay in the intensive care unit.
结局指标
主要结局
development of pressure injury after admission to intensive care unit until discharge
时间窗: after admission of patients to the intensive care unit until discharge between from March 2021 to May 2022. .
The development of pressure injuries after admission of patients to the intensive care unit until discharge between from March 2021 to May 2022. . This is a retrospective study, so there is no specific time. We specified time frame details below.
次要结局
未报告次要终点
研究者
Ayda Kebapci
Associate Professor
Koç University