Treatment of Melasma With Jessner's Solution vs. Trichloroacetic Acid: A Comparison of Clinical Efficacy
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 19
- 试验地点
- 1
- 主要终点
- Clinical efficacy by clinician's evaluation
研究概览
简要总结
Melasma is an acquired discoloration of the skin characterized by brown patches. Chemical peels using agents such as Jessner's solution and trichloroacetic acid (TCA) are commonly used to treat melasma. A chemical peel involves applying the peeling agent to the skin for a short period. The skin will peel similar to a sunburn, and moisturizers are applied to the skin. Although both agents are well-accepted, there have been no good comparisons of the two agents. The purpose of this study is determine if there is a difference in the effectiveness of these two agents.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adults > 18 years old
- •Clinical diagnosis of melasma
- •Mental capacity to give informed consent
排除标准
- •Pregnancy
- •H/o allergy to Jessner's solution, tricholoracetetic acid, tretinoin, or hydroquinone
- •Active dermatitis
- •Presence of cutaneous infection
研究组 & 干预措施
Chemical Peel
Split face treatment paradigm
干预措施: Jessner's solution chemical peel (Procedure)
Chemical Peel
Split face treatment paradigm
干预措施: Trichloroacetic acid chemical peel (Procedure)
结局指标
主要结局
Clinical efficacy by clinician's evaluation
时间窗: 3 months
Hyperpigmenation Global Score
次要结局
- Efficacy by subject's evaluation(3 months)
研究者
Zakiya Rice
Principal Investigator
Emory University