Considerations on the Transfusion Threshold in Cardiac Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 852
- 试验地点
- 1
- 主要终点
- Hemoglobin rate
研究概览
简要总结
This is a retrospective observational study of the transfusion threshold in cardiac surgery.
There is controversy in the literature regarding the transfusion threshold to be adopted, especially in a patient who has undergone cardiac surgery. Some authors suggest that the transfusion should be done in a restrictive way when a certain threshold in hemoglobin is reached, in order to avoid the risks it implies, especially infectious.This threshold is very controversial and remains to be defined (variations in the literature from 7g / dL to 9g / dL). Other authors conclude that there is no superiority of a restrictive transfusion compared to a more liberal transfusion, with regard to the morbidity or medical costs.
It is therefore interesting to study, in a retrospective manner, the global and multidisciplinary management of patients who have undergone a cardiac surgery within the CHU Brugmann hospital, to analyze if they have been adequately transfused.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients having undergone cardiac surgery (other than the placement of a pacemaker or defibrillator) within the CHU Brugmann hospital between 2006 and 2015
排除标准
- 未提供
结局指标
主要结局
Hemoglobin rate
时间窗: Five days after surgery (J5)
Hemoglobin rate
Liquid balance
时间窗: One day after surgery
Ratio between total fluid intake (perfusion) and loss (blood and urine)
Hematocrit rate
时间窗: Five days after surgery (J5)
Hematocrit rate
Creatinin rate
时间窗: Five days after surgery (J5)
Renal function indicator
International Normalized Ratio (INR)
时间窗: Five days after surgery (J5)
Coagulation indicator
Total amount of blood perfusions
时间窗: Five days after surgery (J5)
Total amount of blood perfusions
次要结局
未报告次要终点
研究者
Pierre Wauthy
Head of clinic
Brugmann University Hospital
